Triple G 12 mg
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1-2 working days
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Chemical reagent
CAS: 2381089-83-2
Price: 649,00 579.00 zł
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Retatrutide – reagent, characteristics
Retatrutide (LY3437943) is a synthetic peptide for research use, characterised by a modified amino acid sequence. In the scientific literature, it is described as a triple agonist of the GLP-1, GIP and glucagon receptors (GCGR). From a chemical and functional perspective, it is an advanced research compound designed to simultaneously activate several key metabolic pathways. Compared with peptides such as tirzepatyd or semaglutide, retatrutide exhibits a broader receptor profile, including an additional glucagon receptor, and therefore remains an important target for research into glucose metabolism, energy balance and lipid metabolism.
The functional structure of retatrutide has been designed to enhance metabolic stability and prolong the molecule’s duration of action, which is significant in studies of long-term modulation of metabolic processes. For this reason, Triple G can be described as a research material intended for laboratory use, including as a reference standard and analytical material in quality control procedures and instrumental analyses, such as HPLC.
Mechanism of retatrutide receptor interaction
According to the results of preclinical and clinical studies, retatrutide acts as a triple agonist of the GLP-1, GIP and GCGR receptors, influencing the regulation of appetite, glucose metabolism and energy expenditure. Activation of the GLP-1 and GIP pathways is associated with improved glycaemic control and reduced energy intake, whilst the role of the glucagon receptor is being investigated in relation to increased energy expenditure and lipid metabolism. Clinical trials have also reported improvements in glycaemic parameters, including HbA1c, and favourable changes in selected metabolic markers.
More recent analyses of retatrutide also indicate that the observed changes in body composition largely involved a reduction in body fat with relative maintenance of lean mass. Therefore, retatrutide remains one of the more advanced research peptides analysed in the area of metabolic endocrinology, body weight control and energy balance.
See also Triple G reagent in 8 mg in a pen-type dosing device
The use of retatrutide in laboratory procedures
Retatrutide can be described as an RUO research reagent used in analyses on incretin signalling, glucose metabolism, energy balance and lipid metabolism. The molecule can act as a reference material in comparative studies, stability tests, qualitative analyses and instrumental procedures such as HPLC. Due to its triple receptor profile, it remains a particularly interesting compound for research projects involving complex metabolic mechanisms.
Scientific sources:
- PubMed ID (PMID): 37366315 Jastreboff A.M. et al.
- PubMed ID (PMID): 38323122 Naeem M. et al.
- PubMed ID (PMID): 37385280 - retatrutide clinical trials
- PubMed ID (PMID): 40609566
The product is intended for scientific research and laboratory analysis. All articles and information on this website are for informational and educational purposes only.
Specification:
Download the safety data sheet
| Parameter | Value |
|---|---|
| Product name | Triple G 12 mg vial |
| Catalogue number | 3862749-12-04 |
| CAS number | 2381089-83-2 |
| Brand | Novell |
| Category | Test compound/chemical reagent |
| Molecular target | GLP-1 / GIP / GCGR receptors |
| Sequence | modified research peptide; sequence as per batch specification / COA |
| Summary formula | C221H342N46O68 |
| Molar mass | approx. 4731.33 g/mol |
| Cleanliness | ≥99% HPLC / according to batch COA |
| Confirmation of identity | MS mass spectrometry / HPLC analysis / batch COA |
| Form | lyophilised powder in a vial |
| Unit quantity | Each vial contains 12 mg of the test compound. Quantity adapted for multiple laboratory tests and comparative analyses. |
| Concentration | according to batch / COA specifications |
| Buffer/Carrier | not applicable - lyophilised form |
| pH of the solution | according to batch COA / not applicable for dry form |
| Storage conditions | Store in a cool, dry and shaded place. After opening or reconstitution, store in the refrigerator and protect from light. |
| Stability after opening | according to laboratory protocol/batch COA |
| COA per batch | certificate of analysis available for each batch of product |
| Application | exclusively for laboratory tests, reference analyses and research-grade applications |
| Important information | This product is classified as a chemical reagent intended solely for scientific research, laboratory analysis and reference purposes. It is not a medicinal product, a food supplement or a foodstuff. It is not intended for use, administration or consumption by humans or animals, nor for diagnostic or therapeutic purposes. The purchaser is obliged to use the product in accordance with its intended purpose, applicable regulations and relevant laboratory procedures. The seller shall not be liable for the consequences of using the product contrary to its declared purpose, subject to mandatory provisions of law. |
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