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Triple G 4 mg vial

Retatrutyd Triple G 4mg | nowoczesny odczynnik badawczy

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Chemical reagent

CAS: 2381089-83-2 

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Price: 379,00 299.00 00zł

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Retatrutyd Triple G – product characteristics

Retatrutyd Triple G It is a synthetic research peptide with a complex sequence structure, described in the scientific literature as a multi-receptor agonist of metabolic pathways. From a research perspective, its agonist profile with regard to receptors is of particular significance GLP-1, GIP and glucagon, which enables the assessment of the relationships between the activation of several receptor systems and the changes observed in metabolic models. In preclinical and clinical studies, Retatrutyd Triple G is being evaluated in the context of incretin signalling, glucose homeostasis, glucose-dependent insulinotropic response, lipid metabolism and the regulation of energy balance. The available scientific data describe retatrutyd as a molecule with a triple receptor profile, making it an interesting research model for studies into the pharmacology of metabolic peptides and incretin receptors. Compared with other peptides with a similar receptor profile, retatrutide is being investigated as a compound with a broader range of activity across metabolic pathways, which is the subject of further research.

See also Triple G 8 mg 


Retatrutide peptide in receptor assays

Retatrutyd Triple G It is a synthetic research peptide being studied in the context of multi-receptor modulation of metabolic pathways. From a research perspective, its agonist profile with regard to receptors is of particular significance GLP-1, GIP and glucagon, which enables the assessment of the relationships between the activation of several signalling pathways and the body’s metabolic response. Unlike compounds that target a single receptor, retatrutide serves as a model for research into the complex regulation of glucose homeostasis, lipid metabolism and energy balance.

In receptor-based analyses, the GLP-1 pathway is primarily examined in relation to the regulation of glucose-dependent insulin secretion, the inhibition of glucagon signalling, and mechanisms involved in appetite control. The GIP pathway is studied in the context of the postprandial metabolic response, insulin secretion and interactions with GLP-1 signalling. Activity at the glucagon receptor, on the other hand, is analysed in studies on energy expenditure, lipid metabolism and the utilisation of energy substrates.

In scientific reports and clinical trials, a titration model was used to assess tolerance, safety and metabolic response as the concentration of the active substance was increased. Below you will find scientific sources and studies, together with the dosing regimens:

-Phase 2 studies: New England Journal of Medicine
-Escalation protocol : SIO Società Italiana Obesità


Scientific data: https://pubmed.ncbi.nlm.nih.gov/37366315/

Retatrutyd Triple G 4mg | nowoczesny odczynnik badawczy

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ParameterValue
Product nameTriple G 4 mg vial
Catalogue number3862749-04-05
CAS number2381089-83-2
BrandNovell
CategoryTest compound/chemical reagent
Molecular targetGLP-1 / GIP / GCGR receptors
Sequencemodified research peptide; sequence as per batch specification / COA
Summary formulaC221H342N46O68
Molar massapprox. 4731.33 g/mol
Cleanliness≥99% HPLC / according to batch COA
Confirmation of identityMS mass spectrometry / HPLC analysis / batch COA
Forma clear solution in a vial
Unit quantityEach vial contains 4 mg of the test compound. Quantity adapted for multiple laboratory tests and comparative analyses.
Concentrationaccording to batch / COA specifications
Buffer/Carrierlaboratory solution / carrier in accordance with the batch specification
pH of the solutionin accordance with the batch COA
Storage conditionsStore in a cool, dry, and dark place. Once opened, keep in the fridge and protect from light.
Stability after openingaccording to laboratory protocol/batch COA
COA per batchcertificate of analysis available for each batch of product
Applicationexclusively for laboratory tests, reference analyses and research-grade applications
Important informationThis product is classified as a chemical reagent intended solely for scientific research, laboratory analysis and reference purposes. It is not a medicinal product, a food supplement or a foodstuff. It is not intended for use, administration or consumption by humans or animals, nor for diagnostic or therapeutic purposes. The purchaser is obliged to use the product in accordance with its intended purpose, applicable regulations and relevant laboratory procedures. The seller shall not be liable for the consequences of using the product contrary to its declared purpose, subject to mandatory provisions of law.

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